Vitamin D is a fat-soluble vitamin that is essential for maintaining healthy bones and teeth, supporting the immune system, brain, and nervous system, and regulating insulin levels. It also influences the expression of genes involved in cancer development. High-dose vitamin D therapy involves taking larger-than-standard doses of vitamin D to treat or prevent certain health conditions. Vitamin D Deficiency, Osteoporosis and Some autoimmune diseases, cardiovascular diseases, and mood disorders have been associated with low vitamin D levels, and high-dose therapy might be considered.
How is the treatment performed?
we follow a modified protocol where we give vitamin-D supplement ,
10000 to 600000 IU of Vitamin D a day based on the patients condition.
Monitoring
Blood Levels: Regular monitoring of blood levels of 25-hydroxyvitamin D is recommended to ensure appropriate dosing and to avoid toxicity.
Ionic Calcium Levels: Monitoring serum calcium levels can help prevent hypercalcemia.
Intact parathyroid hormone levels: PTH plays a key role regulating calcium levels, PTH and Vitamin D form a tightly controlled feedback cycle
What health problems can vitamin D therapy be used for?
1. Bone Health: Vitamin D is essential for calcium absorption and bone mineralization, helping prevent rickets in children and osteomalacia and osteoporosis in adults.
2. Immune Support: Adequate vitamin D levels support immune function, potentially reducing the risk of infections.
3. Muscle Function: Vitamin D plays a role in muscle function, and deficiency can lead to muscle weakness.
4. Mood Regulation: Some studies suggest that vitamin D may play a role in mood regulation and the prevention of depression.
5. Chronic Disease Prevention: There is evidence that adequate vitamin D levels may help prevent certain chronic diseases, such as cardiovascular disease and certain cancers.
Research corner
Charoenngam N. Vitamin D and Rheumatic Diseases: A Review of Clinical Evidence. Int J Mol Sci. 2021 Oct 1;22(19):10659. doi: 10.3390/ijms221910659. PMID: 34639000; PMCID: PMC8508879.
Barrea L, Savanelli MC, Di Somma C, Napolitano M, Megna M, Colao A, Savastano S. Vitamin D and its role in psoriasis: An overview of the dermatologist and nutritionist. Rev Endocr Metab Disord. 2017 Jun;18(2):195-205. doi: 10.1007/s11154-017-9411-6. PMID: 28176237; PMCID: PMC5486909.